Journal article
CircRNAs: role in human diseases and potential use as biomarkers
Abstract
Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively low but due to the circular configuration, their stability is very high. In addition, circRNAs display high degree of tissue specificity. The sponging activity of circRNAs toward microRNAs is the best-described mode of action of circRNAs. However, the ability of …
Authors
Verduci L; Tarcitano E; Strano S; Yarden Y; Blandino G
Journal
Cell Death & Disease, Vol. 12, No. 5,
Publisher
Springer Nature
DOI
10.1038/s41419-021-03743-3
ISSN
2041-4889