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Induction of Bystander Response in Human Glioma...
Journal article

Induction of Bystander Response in Human Glioma Cells using High-Energy Electrons: A Role for TGF-1

Abstract

We examined bystander cell death produced in T98G cells by exposure to irradiated cell conditioned medium (ICCM) produced by high-energy 20 MeV electrons at a dose rate of 10 Gy min(-1) and doses up to 20 Gy. ICCM induced a bystander response in T98G glioma cells, reducing recipient cell survival by more than 25% below controls at 5 and 10 Gy. Higher doses increased survival to near control levels. ICCM was analyzed for the presence of …

Authors

Gow MD; Seymour CB; Ryan LA; Mothersill CE

Journal

Radiation Research, Vol. 173, No. 6, pp. 769–778

Publisher

Radiation Research Society

Publication Date

6 2010

DOI

10.1667/rr1895.1

ISSN

0033-7587