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An Observed Effect of p53 Status on the Bystander...
Journal article

An Observed Effect of p53 Status on the Bystander Response to Radiation-Induced Cellular Photon Emission

Abstract

In this study, we investigated the potential influence of p53 on ultraviolet (UV) signal generation and response of bystander cells to the UV signals generated by beta-irradiated cells. Five cell lines of various p53 status (HaCaT, mutated; SW48, wild-type; HT29, mutated; HCT116+/+, wild-type; HCT116-/-, null) were irradiated with beta particles from tritium. Signal generation (photon emission at 340 ± 5 nm) was quantified from irradiated cells …

Authors

Le M; Mothersill CE; Seymour CB; Rainbow AJ; McNeill FE

Journal

Radiation Research, Vol. 187, No. 2, pp. 169–185

Publisher

Radiation Research Society

Publication Date

2 2017

DOI

10.1667/rr14342.1

ISSN

0033-7587