Journal article
Cell-specific drug targeting in the lung
Abstract
Non-targeted drug delivery systems have several limitations including the decreased bioavailability of the drug, poor stability and rapid clearance in addition to off-target distribution. Cell-specific targeted delivery approaches promise to overcome some of these limitations and enhance therapeutic selectivity. In this review, we aim to discuss cell-specific targeted approachesin the lung at the biochemical and molecular levels. These …
Authors
Abed S; Turner R; Serniuck N; Tat V; Naiel S; Hayat A; Mekhael O; Vierhout M; Ask K; Rullo AF
Journal
Biochemical Pharmacology, Vol. 190, ,
Publisher
Elsevier
Publication Date
8 2021
DOI
10.1016/j.bcp.2021.114577
ISSN
0006-2952