Chapter
Does My Bias Look Big in This?
Abstract
Randomised controlled trials (RCTs) are thought to be the gold standard in evidence. This review of their origins and adoption, highlights commonly ignored shortcomings with RCTs. If RCTs are used indiscriminately, their adverse effects may outweigh their benefits. This chapter focuses on antidepressants and how RCTs give the wrong message about safety, efficacy, and effectiveness. The arguments hold true in principle for all treatments, …
Authors
Healy D; Mangin D
Book title
Clinical Research Involving Pregnant Women
Series
Research Ethics Forum
Volume
3
Pagination
pp. 197-208
Publisher
Springer Nature
Publication Date
2016
DOI
10.1007/978-3-319-26512-4_11