Regulation of prostaglandin E and F production in the goldfish testis

Abstract The present studies have investigated the putative role of activators of different signal transduction pathways in the regulation of prostaglandin (PG) production by goldfish testis pieces in vitro. The protein kinase C activator (PKC) phorbol 12‐myristate 13‐acetate (PMA: 1.56‐400 nM) and calcium ionophore A23187 (62.5‐4000 nM) stimulated PGE and F production in a dose and time‐dependent fashion. There was no synergism between A23187 …