Journal article
Identification of a Locus on the X Chromosome Linked to Familial Membranous Nephropathy
Abstract
INTRODUCTION: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome (NS) in adults and is a leading cause of end-stage renal disease due to glomerulonephritis. Primary MN has a strong male predominance, accounting for approximately 65% of cases; yet, currently associated genetic loci are all located on autosomes. Previous reports of familial MN have suggested the existence of a potential X-linked susceptibility locus. …
Authors
Downie ML; Gupta S; Tekman MC; Cheshire C; Arora S; Licht C; Robinson LA; Munoz M; Aris AM; Al Attrach I
Journal
Kidney International Reports, Vol. 6, No. 6, pp. 1669–1676
Publisher
Elsevier
Publication Date
June 2021
DOI
10.1016/j.ekir.2021.02.025
ISSN
2468-0249