Journal article
Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART
Abstract
BackgroundThe 2018 World Health Organization HIV guidelines were based on the results of a network meta-analysis (NMA) of published trials. This study employed individual patient-level data (IPD) and aggregate data (AgD) and meta-regression methods to assess the evidence supporting the WHO recommendations and whether they needed any refinements.MethodsAccess to IPD from three trials was granted through ClinicalStudyDataRequest.com (CSDR). Seven …
Authors
Kanters S; Karim ME; Thorlund K; Anis AH; Zoratti M; Bansback N
Journal
BMC Medical Research Methodology, Vol. 21, No. 1,
Publisher
Springer Nature
Publication Date
12 2021
DOI
10.1186/s12874-021-01254-5
ISSN
1471-2288