Journal article
Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model
Abstract
BACKGROUND: The use of whole blood (WB) to treat trauma patients is becoming more common. Similar to the treatment of individual components, pathogen inactivation (PI) technologies are available to treat WB. The impact of PI on WB function is not well understood. This study investigated the impact of PI of WB with riboflavin/ultraviolet (UV) light on its hemostatic function by modeling transfusion scenarios for trauma patients and assessing …
Authors
Arbaeen AF; Schubert P; Sheffield WP; Devine DV
Journal
Transfusion, Vol. 61, No. 6, pp. 1884–1893
Publisher
Wiley
Publication Date
June 2021
DOI
10.1111/trf.16382
ISSN
0041-1132