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Efficacy and safety of low-dose colchicine in...
Journal article

Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials

Abstract

AIMS: Recent randomized trials demonstrated a benefit of low-dose colchicine added to guideline-based treatment in patients with recent myocardial infarction or chronic coronary disease. We performed a systematic review and meta-analysis to obtain best estimates of the effects of colchicine on major adverse cardiovascular events (MACE). METHODS AND RESULTS: We searched the literature for randomized clinical trials of long-term colchicine in …

Authors

Fiolet ATL; Opstal TSJ; Mosterd A; Eikelboom JW; Jolly SS; Keech AC; Kelly P; Tong DC; Layland J; Nidorf SM

Journal

European Heart Journal, Vol. 42, No. 28, pp. 2765–2775

Publisher

Oxford University Press (OUP)

Publication Date

July 21, 2021

DOI

10.1093/eurheartj/ehab115

ISSN

0195-668X