Journal article
CSF free light chain identification of demyelinating disease: comparison with oligoclonal banding and other CSF indexes
Abstract
BACKGROUND: Cerebrospinal fluid (CSF) used in immunoglobulin gamma (IgG) index testing and oligoclonal bands (OCBs) are common laboratory tests used in the diagnosis of multiple sclerosis. The measurement of CSF free light chains (FLC) could pose as an alternative to the labor-intensive isoelectric-focusing (IEF) gels used for OCBs.
METHODS: A total of 325 residual paired CSF and serum specimens were obtained after physician-ordered OCB IEF …
Authors
Gurtner KM; Shosha E; Bryant SC; Andreguetto BD; Murray DL; Pittock SJ; Willrich MAV
Journal
Clinical Chemistry and Laboratory Medicine, Vol. 56, No. 7, pp. 1071–1080
Publisher
De Gruyter
Publication Date
June 27, 2018
DOI
10.1515/cclm-2017-0901
ISSN
1434-6621