Reply to: Noxious cold stimulation: pro–con perspectives on the hypothermic effect on experimentally evoked cough

We thank S. Zhong and co-workers for their interest and thoughtful letter in response to our manuscript, “The effect of pain conditioning on experimentally evoked cough: evidence of impaired endogenous inhibitory control mechanisms in refractory chronic cough” [1]. In this study we demonstrated that a painful cold stimulus, applied to the hand, inhibited cough responses to capsaicin in humans, and that this phenomenon (known as conditioned pain …