Journal article
The pharmacokinetics of epinephrine/adrenaline autoinjectors
Abstract
BackgroundFor a century, epinephrine has been the drug of choice for acute treatment of systemic allergic reactions/anaphylaxis. For 40 years, autoinjectors have been used for the treatment of anaphylaxis. Over the last 20 years, intramuscular epinephrine injected into the thigh has been recommended for optimal effect.ObjectiveTo review the literature on pharmacokinetics of epinephrine autoinjectors.ResultsSix studies assessing epinephrine …
Authors
Dreborg S; Kim H
Journal
Allergy, Asthma & Clinical Immunology, Vol. 17, No. 1,
Publisher
Springer Nature
Publication Date
December 2021
DOI
10.1186/s13223-021-00511-y
ISSN
1710-1484