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A Cross-Linking Approach to Stabilizing...
Journal article

A Cross-Linking Approach to Stabilizing Stimuli-Responsive Colloidal Crystals Engineered with DNA

Abstract

Two DNA-cross-linking reagents, bis-chloroethylnitrosourea and 8-methoxypsoralen, are used to covalently cross-link interstrand base pairs in DNA bonds that, in part, define colloidal crystals engineered with DNA. The irreversible linkages formed increase the chemical and thermal stability of the crystals and do not significantly affect their long-range order, as evidenced by small-angle X-ray scattering data. The post-modified crystals are …

Authors

Lee S; Zheng CY; Bujold KE; Mirkin CA

Journal

Journal of the American Chemical Society, Vol. 141, No. 30, pp. 11827–11831

Publisher

American Chemical Society (ACS)

Publication Date

July 31, 2019

DOI

10.1021/jacs.9b06106

ISSN

0002-7863