Journal article
Severe thrombophilia in a factor V‐deficient patient homozygous for the Ala2086Asp mutation (FV Besançon)
Abstract
BACKGROUND: Coagulation factor V (FV), present in plasma and platelets, has both pro- and anticoagulant functions.
OBJECTIVE: We investigated an FV-deficient patient (FV:C 3%, FV:Ag 4%) paradoxically presenting with recurrent venous thrombosis (11 events) instead of bleeding.
Authors
Castoldi E; Hézard N; Mourey G; Wichapong K; Poggi M; Ibrahim-Kosta M; Thomassen MCLGD; Fournel A; Hayward CPM; Alessi M-C
Journal
Journal of Thrombosis and Haemostasis, Vol. 19, No. 5, pp. 1186–1199
Publisher
Elsevier
Publication Date
May 2021
DOI
10.1111/jth.15274
ISSN
1538-7933