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Characterization of ADAMTS13 and von Willebrand...
Journal article

Characterization of ADAMTS13 and von Willebrand factor levels in septic and non-septic ICU patients

Abstract

Sepsis is a life-threatening disease characterized by excessive host response to infection that can lead to activation of the coagulation system. Von Willebrand Factor (VWF) and ADAMTS13 are important regulators of hemostasis and their dysregulation during sepsis progression is not well understood. Herein we characterize ADAMTS13 and VWF in septic and non-septic patients. ADAMTS13 activity, ADAMTS13 antigen, VWF antigen, myeloperoxidase, and …

Authors

Singh K; Kwong AC; Madarati H; Kunasekaran S; Sparring T; Fox-Robichaud AE; Liaw PC; Kretz CA

Journal

PLOS ONE, Vol. 16, No. 2,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0247017

ISSN

1932-6203