Journal article
Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder
Abstract
Using a novel trait-based measure, we examined genetic variants associated with obsessive-compulsive (OC) traits and tested whether OC traits and obsessive-compulsive disorder (OCD) shared genetic risk. We conducted a genome-wide association analysis (GWAS) of OC traits using the Toronto Obsessive-Compulsive Scale (TOCS) in 5018 unrelated Caucasian children and adolescents from the community (Spit for Science sample). We tested the hypothesis …
Authors
Burton CL; Lemire M; Xiao B; Corfield EC; Erdman L; Bralten J; Poelmans G; Yu D; Shaheen S-M; Goodale T
Journal
Translational Psychiatry, Vol. 11, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41398-020-01121-9
ISSN
2158-3188