Journal article
Genomic and Clinical Correlates of Adrenocortical Carcinoma in an Adult Patient with Li-Fraumeni Syndrome: A Case Report
Abstract
Li-Fraumeni Syndrome (LFS) is defined by germline mutations of the p53 tumour suppressor gene. Adrenocortical carcinoma (ACC) is a rare aggressive malignancy that is commonly associated with LFS. Most LFS-linked ACC cases occur in children, and limited research has been dedicated to the clinical outcomes and genomics of adult cases with LFS-linked ACC. We report on a 34-year-old female who was diagnosed with three separate malignancies: stage …
Authors
Bondy S; Tajzler C; Hotte SJ; Kapoor A; Zbuk K; Lalani A-KA
Journal
Current Oncology, Vol. 28, No. 1, pp. 226–232
Publisher
MDPI
DOI
10.3390/curroncol28010025
ISSN
1198-0052