Journal article
A critical role for IL‐15 in TLR‐mediated innate antiviral immunity against genital HSV‐2 infection
Abstract
Innate antiviral immunity, particularly at mucosal surfaces, has a critical role in early control of viral infections. Both type I interferons (IFNs) and interleukin-15 (IL-15) are essential components of innate antiviral immunity. It has been shown that toll-like receptor (TLR) ligand-induced innate antiviral immunity requires IFN-α/β and -λ receptor signaling. However, it is not known if IL-15 has a role in TLR ligand-mediated antiviral …
Authors
Thatte A; DeWitte‐Orr SJ; Lichty B; Mossman KL; Ashkar AA
Journal
Immunology and Cell Biology, Vol. 89, No. 6, pp. 663–669
Publisher
Wiley
Publication Date
8 2011
DOI
10.1038/icb.2011.7
ISSN
0818-9641