Journal article
Herpes simplex virus-2 in the genital mucosa
Abstract
PURPOSE OF REVIEW: Herpes simplex virus (HSV)-2 is the predominant cause of genital herpes and has been implicated in HIV infection and transmission. Thus far, vaccines developed against HSV-2 have been clinically ineffective in preventing infection. This review aims to summarize the innate and adaptive immune responses against HSV-2 and examines the current status of vaccine development.
RECENT FINDINGS: Both innate and adaptive immune …
Authors
Lee AJ; Ashkar AA
Journal
Current Opinion in Infectious Diseases, Vol. 25, No. 1, pp. 92–99
Publisher
Wolters Kluwer
Publication Date
2 2012
DOI
10.1097/qco.0b013e32834e9a56
ISSN
0951-7375