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The Fragility of Statistically Significant...
Journal article

The Fragility of Statistically Significant Findings From Randomized Controlled Trials in Hip and Knee Arthroplasty

Abstract

BACKGROUND: The Fragility Index (FI) is a method for evaluating the robustness of statistically significant findings from randomized controlled trials (RCTs) beyond the P value in trials with dichotomous outcomes. The FI is defined as the number of patients in one arm of a trial that would have to have a different outcome to change the results of the trial from statistically significant to nonsignificant. This review assessed the FI in …

Authors

Ekhtiari S; Gazendam AM; Nucci NW; Kruse CC; Bhandari M

Journal

The Journal of Arthroplasty, Vol. 36, No. 6, pp. 2211–2218.e1

Publisher

Elsevier

Publication Date

6 2021

DOI

10.1016/j.arth.2020.12.015

ISSN

0883-5403