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Long-Term Follow-up of Tisagenlecleucel in Adult...
Conference

Long-Term Follow-up of Tisagenlecleucel in Adult Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Updated Analysis of Juliet Study

Abstract

Background Tisagenlecleucel, a chimeric antigen receptor T-cell therapy, has demonstrated efficacy and manageable safety in adult patients (pts) with relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL) in the global, multicenter, pivotal, phase 2, JULIET trial (NCT02445248). The primary endpoint, overall response rate (ORR), was met at the interim analysis (ORR: 59% [CR, 43%; PR, 16%]). Here, we report an updated analysis with a …

Authors

Schuster SJ; Bishop MR; Tam CS; Borchmann P; Jaeger U; Waller EK; Holte H; McGuirk J; Jaglowski S; Tobinai K

Volume

25

Pagination

pp. s20-s21

Publisher

Elsevier

Publication Date

March 2019

DOI

10.1016/j.bbmt.2018.12.089

Conference proceedings

Transplantation and Cellular Therapy

Issue

3

ISSN

2666-6367