Conference
Abstract A100: Seamless phase I/II clinical trials in oncology: retrospective analysis of the last 7 years
Abstract
Abstract
Introduction: Drug development has evolved from the conventional sequence of three-phase clinical trial process to a seamless approach of adding cohorts to first-in-human trials to investigate both safety and efficacy in various cancers. In this retrospective study, we evaluated the prevalence of large early-phase studies in adult cancer patients; described the clinical characteristics, design, and statistical plan of …
Authors
Barata P; Hobbs B; Rini B; Paller C; Normolle D; Garrett-Mayer E; Rubin E; Rosner G; Pond G; Perlmutter J
Volume
17
Pagination
pp. a100-a100
Publisher
American Association for Cancer Research (AACR)
Publication Date
January 1, 2018
DOI
10.1158/1535-7163.targ-17-a100
Conference proceedings
Molecular Cancer Therapeutics
Issue
1_Supplement
ISSN
1535-7163