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Biomarkers of inflammation and repair in kidney...
Journal article

Biomarkers of inflammation and repair in kidney disease progression

Abstract

INTRODUCTIONAcute kidney injury and chronic kidney disease (CKD) are common in hospitalized patients. To inform clinical decision making, more accurate information regarding risk of long-term progression to kidney failure is required.METHODSWe enrolled 1538 hospitalized patients in a multicenter, prospective cohort study. Monocyte chemoattractant protein 1 (MCP-1/CCL2), uromodulin (UMOD), and YKL-40 (CHI3L1) were measured in urine samples …

Authors

Puthumana J; Thiessen-Philbrook H; Xu L; Coca SG; Garg AX; Himmelfarb J; Bhatraju PK; Ikizler TA; Siew E; Ware LB

Journal

Journal of Clinical Investigation, Vol. 131, No. 3,

Publisher

American Society for Clinical Investigation

Publication Date

February 1, 2021

DOI

10.1172/jci139927

ISSN

0021-9738