Journal article
Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK
Abstract
BACKGROUND: Inflammatory bowel diseases are the most common chronic intestinal inflammatory conditions, and their incidence has shown a dramatic increase in recent decades. Limited efficacy and questionable safety profiles with existing therapies suggest the need for better targeting of therapeutic strategies. Adenosine monophosphate-activated protein kinase (AMPK) is a key regulator of cellular metabolism and has been implicated in intestinal …
Authors
Banskota S; Wang H; Kwon YH; Gautam J; Gurung P; Haq S; Hassan FMN; Bowdish DM; Kim J-A; Carling D
Journal
Inflammatory Bowel Diseases, Vol. 27, No. 6, pp. 914–926
Publisher
Oxford University Press (OUP)
Publication Date
May 17, 2021
DOI
10.1093/ibd/izaa305
ISSN
1078-0998