Journal article
Factors affecting stability of plasma brain-derived neurotrophic factor
Abstract
Circulating concentrations of brain-derived neurotrophic factor (BDNF) have been linked to cancer, neuropsychiatric, diabetes, and gynecological disorders. However, factors influencing plasma storage and subsequent BDNF quantification are incompletely understood. Therefore, the anticoagulant used in plasma separator tubes, storage-time, storage-temperature, and repeated freeze–thaw cycles on circulating BDNF concentrations was evaluated. …
Authors
Wessels JM; Agarwal RK; Somani A; Verschoor CP; Agarwal SK; Foster WG
Journal
Scientific Reports, Vol. 10, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41598-020-77046-6
ISSN
2045-2322