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A large-scale genome-wide association study...
Journal article

A large-scale genome-wide association study meta-analysis of cannabis use disorder

Abstract

BACKGROUND: Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50-70%) and is associated with negative outcomes, including increased risk of psychopathology. The aim of the study was to conduct a large genome-wide association study (GWAS) to identify novel genetic variants associated with cannabis use disorder. METHODS: To conduct this GWAS meta-analysis of cannabis use …

Authors

Johnson EC; Demontis D; Thorgeirsson TE; Walters RK; Polimanti R; Hatoum AS; Sanchez-Roige S; Paul SE; Wendt FR; Clarke T-K

Journal

The Lancet Psychiatry, Vol. 7, No. 12, pp. 1032–1045

Publisher

Elsevier

Publication Date

December 2020

DOI

10.1016/s2215-0366(20)30339-4

ISSN

2215-0366