Anticoagulation of Pregnant Women With Mechanical Heart Valves: A Systematic Review of the Literature

Abstract

BACKGROUND: The management of women with prosthetic heart valves during pregnancy poses a particular challenge as there are no available controlled clinical trials to provide guidelines for effective antithrombotic therapy. Oral anticoagulants such as warfarin sodium cause fetal embryopathy; subcutaneous administration of heparin sodium has been reported to be ineffective in preventing thromboembolic complications. OBJECTIVE: To identify the …

Authors

Chan WS; Anand S; Ginsberg JS

Journal

JAMA Internal Medicine, Vol. 160, No. 2, pp. 191–196

Publisher

American Medical Association (AMA)

Publication Date

January 24, 2000

DOI

10.1001/archinte.160.2.191

ISSN

2168-6106

Associated Experts

Sonia Anand

Professor, Faculty of Health Sciences

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