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Association between C reactive protein and...
Journal article

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

Abstract

OBJECTIVE: To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease. DESIGN: Mendelian randomisation meta-analysis of individual participant data from 47 epidemiological studies in 15 countries.

Authors

Wensley F; Gao P; Burgess S; Kaptoge S; Di Angelantonio E; Shah T; Engert JC; Clarke R; Davey-Smith G; Nordestgaard BG

Journal

The BMJ, Vol. 342, No. feb15 2,

Publisher

BMJ

Publication Date

February 15, 2011

DOI

10.1136/bmj.d548

ISSN

0959-8138