Journal article
Single Cell Technologies Define New Therapeutic Avenues for Huntington’s Disease
Abstract
Using two independent single-cell transcriptomics technologies, Lee et al. have cataloged transcriptional changes in the subset of striatal neurons hit hardest in Huntington's disease. One downregulated pathway, oxidative phosphorylation, may also explain their observed release of mitochondrial-encoded RNAs.
Authors
Maiuri T; Truant R
Journal
Neuron, Vol. 107, No. 5, pp. 768–769
Publisher
Elsevier
Publication Date
9 2020
DOI
10.1016/j.neuron.2020.08.007
ISSN
0896-6273