Journal article
Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19
Abstract
As the global COVID-19 pandemic continues, unabated and clinical trials demonstrate limited effective pharmaceutical interventions, there is a pressing need to accelerate treatment evaluations. Among options for accelerated development is the evaluation of drug combinations in the absence of prior monotherapy data. This approach is appealing for a number of reasons. First, combining two or more drugs with related or complementary therapeutic …
Authors
Rayner CR; Dron L; Park JJH; Decloedt EH; Cotton MF; Niranjan V; Smith PF; Dodds MG; Brown F; Reis G
Journal
American Journal of Tropical Medicine and Hygiene, Vol. 103, No. 4, pp. 1364–1366
Publisher
American Society of Tropical Medicine and Hygiene
Publication Date
October 7, 2020
DOI
10.4269/ajtmh.20-0995
ISSN
0002-9637