Journal article
Performance characteristics of screening strategies to identify Lynch syndrome in women with ovarian cancer
Abstract
BACKGROUND: For women with ovarian cancer (OC), the optimal screening strategy to identify Lynch syndrome (LS) has not been determined. In the current study, the authors compared the performance characteristics of various strategies combining mismatch repair (MMR) immunohistochemistry (IHC), microsatellite instability testing (MSI), and family history for the detection of LS.
METHODS: Women with nonserous and/or nonmucinous ovarian cancer were …
Authors
Kim SR; Tone A; Kim RH; Cesari M; Clarke BA; Eiriksson L; Hart T; Aronson M; Holter S; Lytwyn A
Journal
Cancer, Vol. 126, No. 22, pp. 4886–4894
Publisher
Wiley
Publication Date
November 15, 2020
DOI
10.1002/cncr.33144
ISSN
1097-0142