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Serotonin in the gut: Blessing or a curse
Journal article

Serotonin in the gut: Blessing or a curse

Abstract

Serotonin (5-hydroxytryptamine or 5-HT) once most extensively studied as a neurotransmitter of the central nervous system, is seen to be predominantly secreted in the gut. About 95% of 5-HT is estimated to be found in gut mainly within the enterochromaffin cells whereas about 5% is found in the brain. 5-HT is an important enteric signaling molecule and is well known for playing a key role in sensory-motor and secretory functions in the gut. In …

Authors

Banskota S; Ghia J-E; Khan WI

Journal

Biochimie, Vol. 161, , pp. 56–64

Publisher

Elsevier

Publication Date

June 2019

DOI

10.1016/j.biochi.2018.06.008

ISSN

0300-9084