Journal article
Increased Intestinal Permeability Is Associated With Later Development of Crohn’s Disease
Abstract
BACKGROUND & AIMS: Increased intestinal permeability has been associated with Crohn's disease (CD), but it is not clear whether it is a cause or result of the disease. We performed a prospective study to determine whether increased intestinal permeability is associated with future development of CD.
METHODS: We assessed the intestinal permeability, measured by the urinary fractional excretion of lactulose-to-mannitol ratio (LMR) at recruitment …
Authors
Turpin W; Lee S-H; Garay JAR; Madsen KL; Meddings JB; Bedrani L; Power N; Espin-Garcia O; Xu W; Smith MI
Journal
Gastroenterology, Vol. 159, No. 6, pp. 2092–2100.e5
Publisher
Elsevier
Publication Date
December 2020
DOI
10.1053/j.gastro.2020.08.005
ISSN
0016-5085