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Channelopathies Are a Frequent Cause of Genetic...
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Channelopathies Are a Frequent Cause of Genetic Ataxias Associated with Cerebellar Atrophy

Abstract

BACKGROUND: Cerebellar atrophy is a nonspecific imaging finding observed in a number of neurological disorders. Genetic ataxias associated with cerebellar atrophy are a heterogeneous group of conditions, rendering the approach to diagnosis challenging. OBJECTIVES: To define the spectrum of genetic ataxias associated with cerebellar atrophy in a Canadian cohort and the diagnostic yield of exome sequencing for this group of conditions.

Authors

Gauquelin L; Hartley T; Tarnopolsky M; Dyment DA; Brais B; Geraghty MT; Tétreault M; Ahmed S; Rojas S; Choquet K

Volume

7

Pagination

pp. 940-949

Publisher

Wiley

Publication Date

11 2020

DOI

10.1002/mdc3.13086

Conference proceedings

Movement Disorders Clinical Practice

Issue

8

ISSN

2330-1619