Journal article
The association of HTR2A polymorphisms with obsessive-compulsive disorder and its subtypes: A meta-analysis
Abstract
BACKGROUND: Genetic risk factors that contribute to obsessive-compulsive disorder (OCD) have yet to be elucidated. Historically, serotonergic dysfunction has been implicated. Evidence from the literature points towards the serotonin receptor 2A gene (HTR2A) as a primary candidate. Our meta-analysis investigated whether polymorphisms in HTR2A are associated with OCD or its subtypes, based on sex and age of onset.
METHODS: Studies employing …
Authors
Mattina GF; Samaan Z; Hall GB; Steiner M
Journal
Journal of Affective Disorders, Vol. 275, , pp. 278–289
Publisher
Elsevier
Publication Date
10 2020
DOI
10.1016/j.jad.2020.06.016
ISSN
0165-0327