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Ba++ as a gastric stimulant: release of histamine
Journal article

Ba++ as a gastric stimulant: release of histamine

Abstract

Ba++ added to the serosal solution bathing a resting frog stomach increased transmucosal resistance and induced acid secretion. The increase in acid secretion was associated with an increased leak of histamine from the mucosa into the serosal solution. Pretreatment with burimamide inhibited the secretory response to Ba++. After a pulse treatment with Ba++ (2 mM for 5 min), the effects on resistance were transient but the effects on acid …

Authors

Rangachari PK

Journal

American Journal of Physiology, Vol. 229, No. 3, pp. 627–631

Publisher

American Physiological Society

Publication Date

September 1, 1975

DOI

10.1152/ajplegacy.1975.229.3.627

ISSN

0002-9513