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Serum Metabolic Signatures of Chronic...
Journal article

Serum Metabolic Signatures of Chronic Limb-Threatening Ischemia in Patients with Peripheral Artery Disease

Abstract

Peripheral artery disease (PAD) is characterized by the atherosclerotic narrowing of lower limb vessels, leading to ischemic muscle pain in older persons. Some patients experience progression to advanced chronic limb-threatening ischemia (CLTI) with poor long-term survivorship. Herein, we performed serum metabolomics to reveal the mechanisms of PAD pathophysiology that may improve its diagnosis and prognosis to CLTI complementary to the …

Authors

Azab SM; Zamzam A; Syed MH; Abdin R; Qadura M; Britz-McKibbin P

Journal

Journal of Clinical Medicine, Vol. 9, No. 6,

Publisher

MDPI

DOI

10.3390/jcm9061877

ISSN

2077-0383