Journal article
The Prehistory of Antibiotic Resistance
Abstract
Antibiotic resistance is a global problem that is reaching crisis levels. The global collection of resistance genes in clinical and environmental samples is the antibiotic "resistome," and is subject to the selective pressure of human activity. The origin of many modern resistance genes in pathogens is likely environmental bacteria, including antibiotic producing organisms that have existed for millennia. Recent work has uncovered resistance in …
Authors
Perry J; Waglechner N; Wright G
Journal
Cold Spring Harbor Perspectives in Medicine, Vol. 6, No. 6,
Publisher
Cold Spring Harbor Laboratory
Publication Date
6 2016
DOI
10.1101/cshperspect.a025197
ISSN
0079-1024