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Efficacy and safety of convalescent plasma for...
Journal article

Efficacy and safety of convalescent plasma for severe COVID-19 based on evidence in other severe respiratory viral infections: a systematic review and meta-analysis

Abstract

BACKGROUND: The safety and efficacy of convalescent plasma in severe coronavirus disease 2019 (COVID-19) remain uncertain. To support a guideline on COVID-19 management, we conducted a systematic review and meta-analysis of convalescent plasma in COVID-19 and other severe respiratory viral infections. METHODS: In March 2020, we searched international and Chinese biomedical literature databases, clinical trial registries and prepublication …

Authors

Devasenapathy N; Ye Z; Loeb M; Fang F; Najafabadi BT; Xiao Y; Couban R; Bégin P; Guyatt G

Journal

Canadian Medical Association Journal, Vol. 192, No. 27, pp. e745–e755

Publisher

Joule

Publication Date

July 6, 2020

DOI

10.1503/cmaj.200642

ISSN

0820-3946