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Pathological lesions in the spontaneously diabetic...
Journal article

Pathological lesions in the spontaneously diabetic BB Wistar rat: A comprehensive autopsy study

Abstract

A total of 145 BB Wistar diabetic rats, 46 of their nondiabetic siblings, and 43 outbred Wistar rats were autopsied and the frequency of lesions in all organ systems were determined. Common strain-related lesions included pulmonary infections, granulomas, lymphoid hyperplasia, lymphomas, lymphocytopenia, eosinophilia, supradiaphragmatic accessory lobes of the liver, and prostatic atrophy. These suggest some basic strain-related abnormalities of …

Authors

Wright JR; Yates AJ; Sharrna HM; Thibert P

Journal

Metabolism, Vol. 32, No. 7, pp. 101–105

Publisher

Elsevier

Publication Date

July 1983

DOI

10.1016/s0026-0495(83)80021-3

ISSN

0026-0495