Journal article
Comparison of the effects of apixaban and rivaroxaban on prothrombin and activated partial thromboplastin times using various reagents
Abstract
BACKGROUND: Clinical situations occur where expedient assessment of the anticoagulant activity of the direct factor Xa (FXa) inhibitors is required. Although quantitative anti-FXa (FXa) assays can be used to measure plasma levels of apixaban or rivaroxaban, turnaround is often slow and many laboratories do not perform these assays.
OBJECTIVE: We compared the in vitro effects of apixaban and rivaroxaban on two readily available laboratory tests, …
Authors
Dale BJ; Ginsberg JS; Johnston M; Hirsh J; Weitz JI; Eikelboom JW
Journal
Journal of Thrombosis and Haemostasis, Vol. 12, No. 11, pp. 1810–1815
Publisher
Elsevier
Publication Date
November 2014
DOI
10.1111/jth.12720
ISSN
1538-7933