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Model-based clustering of microarray expression...
Journal article

Model-based clustering of microarray expression data via latent Gaussian mixture models

Abstract

MOTIVATION: In recent years, work has been carried out on clustering gene expression microarray data. Some approaches are developed from an algorithmic viewpoint whereas others are developed via the application of mixture models. In this article, a family of eight mixture models which utilizes the factor analysis covariance structure is extended to 12 models and applied to gene expression microarray data. This modelling approach builds on …

Authors

McNicholas PD; Murphy TB

Journal

Bioinformatics, Vol. 26, No. 21, pp. 2705–2712

Publisher

Oxford University Press (OUP)

Publication Date

November 1, 2010

DOI

10.1093/bioinformatics/btq498

ISSN

1367-4803