Journal article
Oncostatin M Induction of Monocyte Chemoattractant Protein 1 is Inhibited by Anti-oncostatin M Receptor Beta Monoclonal Antibody KPL-716
Abstract
To evaluate cellular response to oncostatin M (OSM) in comparison to interleukin (IL)-31, we analyzed monocyte chemoattractant protein 1 (MCP-1) as a readout for OSM responses with and without IL-4, IL-13, anti-OSM receptor β monoclonal antibody KPL-716, and anti-IL-31 receptor α antibody in human epidermal keratinocytes and human dermal fibroblasts in vitro. In human epidermal keratinocytes, OSM significantly induced STAT3 or STAT1 …
Authors
RICHARDS CD; GANDHI R; BOTELHO F; HO L; PAOLINI JF
Journal
Acta Dermato Venereologica, Vol. 100, No. 14,
Publisher
MJS Publishing, Medical Journals Sweden AB
DOI
10.2340/00015555-3505
ISSN
0001-5555