Magnetization transfer ratio and apparent diffusion coefficient analysis in children with global developmental delay

Global developmental delay has a significant socioeconomic impact. Early identification of the etiology can obviate further diagnostic testing. Magnetization transfer imaging and diffusion-weighted imaging were performed on 85 children with global developmental delay and 133 normally developed children as control. Conventional MRI was abnormal in all of the 41 children with congenital brain malformation, metabolic and chromosomal disorders, and …