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Angiogenin Levels and ANG Genotypes: Dysregulation...
Journal article

Angiogenin Levels and ANG Genotypes: Dysregulation in Amyotrophic Lateral Sclerosis

Abstract

OBJECTIVE: To determine whether 5 single nucleotide polymorphisms (SNPs) associate with ALS in 3 different populations. We also assessed the contribution of genotype to angiogenin levels in plasma and CSF. METHODS: Allelic association statistics were calculated for polymorphisms in the ANG gene in 859 patients and 1047 controls from Sweden, Ireland and Poland. Plasma, serum and CSF angiogenin levels were quantified and stratified according to …

Authors

McLaughlin RL; Phukan J; McCormack W; Lynch DS; Greenway M; Cronin S; Saunders J; Slowik A; Tomik B; Andersen PM

Journal

PLOS ONE, Vol. 5, No. 11,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0015402

ISSN

1932-6203