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Hygiene and the world distribution of Alzheimer’s...
Journal article

Hygiene and the world distribution of Alzheimer’s disease

Abstract

BACKGROUND AND OBJECTIVES: Alzheimer's disease (AD) shares certain etiological features with autoimmunity. Prevalence of autoimmunity varies between populations in accordance with variation in environmental microbial diversity. Exposure to microorganisms may improve individuals' immunoregulation in ways that protect against autoimmunity, and we suggest that this may also be the case for AD. Here, we investigate whether differences in microbial …

Authors

Fox M; Knapp LA; Andrews PW; Fincher CL

Journal

Evolution Medicine and Public Health, Vol. 2013, No. 1, pp. 173–186

Publisher

Oxford University Press (OUP)

Publication Date

January 1, 2013

DOI

10.1093/emph/eot015

ISSN

2050-6201