Journal article
RpoE fine tunes expression of a subset of SsrB-regulated virulence factors in Salmonella enterica serovar Typhimurium
Abstract
BackgroundThe survival of Salmonella enterica within the intracellular host niche requires highly co-ordinated expression of virulence effectors predominantly regulated by the SsrAB two-component regulatory system. S. enterica serovar Typhimurium mutants lacking the ssrAB genes are avirulent in mice, highlighting the importance of this regulatory system in vivo. Mutants lacking the gene encoding the alternative sigma factor σE (rpoE) are also …
Authors
Osborne SE; Coombes BK
Journal
BMC Microbiology, Vol. 9, No. 1,
Publisher
Springer Nature
Publication Date
2009
DOI
10.1186/1471-2180-9-45
ISSN
1471-2180