Journal article
Transcriptional Priming of Salmonella Pathogenicity Island-2 Precedes Cellular Invasion
Abstract
Invasive salmonellosis caused by Salmonella enterica involves an enteric stage of infection where the bacteria colonize mucosal epithelial cells, followed by systemic infection with intracellular replication in immune cells. The type III secretion system encoded in Salmonella Pathogenicity Island (SPI)-2 is essential for intracellular replication and the regulators governing high-level expression of SPI-2 genes within the macrophage phagosome …
Authors
Osborne SE; Coombes BK
Journal
PLOS ONE, Vol. 6, No. 6,
Publisher
Public Library of Science (PLoS)
Publication Date
2011
DOI
10.1371/journal.pone.0021648
ISSN
1932-6203