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The role of WNT5A and Ror2 in peritoneal membrane...
Journal article

The role of WNT5A and Ror2 in peritoneal membrane injury

Abstract

Patients on peritoneal dialysis are at risk of developing peritoneal fibrosis and angiogenesis, which can lead to dysfunction of the peritoneal membrane. Recent evidence has identified cross-talk between transforming growth factor beta (TGFB) and the WNT/β-catenin pathway to induce fibrosis and angiogenesis. Limited evidence exists describing the role of non-canonical WNT signalling in peritoneal membrane injury. Non-canonical WNT5A is …

Authors

Padwal M; Liu L; Margetts PJ

Journal

Journal of Cellular and Molecular Medicine, Vol. 24, No. 6, pp. 3481–3491

Publisher

Wiley

Publication Date

March 2020

DOI

10.1111/jcmm.15034

ISSN

1582-1838